Plerixafor use for peripheral blood stem cell mobilization in Korea
نویسندگان
چکیده
Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Department of Oncology, Asan Medical Center, University of Ulsan, Seoul, Department of Internal Medicine, Chonnam National University Hwasun Hospital, Hwasun, Hematologic Malignancy Branch, National Cancer Center, Ilsan, Department of Internal Medicine, St. Mary Hospital, The Catholic University of Korea, Department of Internal Medicine, Seoul National University Hospiltal, Seoul, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea
منابع مشابه
Hematopoietic stem cell mobilization: current status and future perspective
Autologous stem cell transplantation (ASCT), high-dose chemotherapy followed by hematopoietic stem cell rescue, is a widely used therapeutic strategy especially for some patients with hematological malignancies such as malignant lymphoma or multiple myeloma (MM). Because successful ASCT is crucial in these patients for improving overall survival [1], collection of a sufficient number of hematop...
متن کاملPlerixafor as a salvage mobilization strategy for haploidentical peripheral blood allogeneic stem cell transplantation
In allogeneic stem cell mobilization, peripheral blood stem cell mobilization with filgrastim can be considered standard of care. Poor mobilizers may be at risk for inadequate stem cell collection during apheresis. He we present a successful case of salvage plerixafor use with filgrastim in a haploidentical identical transplant patient.
متن کاملPlerixafor plus granulocyte colony-stimulating factor improves the mobilization of hematopoietic stem cells in patients with non-Hodgkin lymphoma and low circulating peripheral blood CD34+ cells.
Many institutions have adopted algorithms based on preapheresis circulating CD34+ cell counts to optimize the use of plerixafor. However, a circulating peripheral blood CD34+ cell threshold that predicts mobilization failure has not been defined. The superiority of plerixafor + granulocyte colony-stimulating factor (G-CSF) over placebo + G-CSF for hematopoietic stem cell mobilization and collec...
متن کاملPlerixafor Salvage Is Safe and Effective in Hard-to-Mobilize Patients Undergoing Chemotherapy and Filgrastim-Based Peripheral Blood Progenitor Cell Mobilization
The combination of filgrastim (G-CSF) and plerixafor is currently approved for mobilizing peripheral blood progenitor cells in patients with non-Hodgkin lymphoma and multiple myeloma undergoing autologous peripheral blood hematopoietic cell transplantation. However, chemotherapy and G-CSF-based mobilization remains a widely used strategy for peripheral blood progenitor cell collection. In this ...
متن کاملPlerixafor in the Treatment of Stem Cell Mobilization Failure; First Experience in Iran
High-dose chemotherapy and autologous stem cell transplantation (SCT) have become an effective care for many patients with hematological malignancies. Harvesting the stem cells is one the most important parts of SCT. The two most commonly used mobilization regimens are the use of granulocyte colony-stimulating factor (G-CSF) or G-CSF plus chemotherapy. However, about 10-30% of patients are unab...
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